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Short-term effects of unilateral lesion of the primary motor cortex (M1) on ipsilesional hand dexterity in adult macaque monkeys

Bashir, Shahid ; Kaeser, Mélanie ; Wyss, Alexander ; Hamadjida, Adjia ; Liu, Yu ; Bloch, Jocelyne ; Brunet, Jean-François ; Belhaj-Saif, Abderraouf ; Rouiller, Eric

In: Brain Structure and Function, 2012, vol. 217, no. 1, p. 63-79

Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys

Hamadjida, Adjia ; Wyss, Alexander ; Mir, Anis ; Schwab, Martin ; Belhaj-Saif, Abderaouf ; Rouiller, Eric

In: Experimental Brain Research, 2012, vol. 223, no. 3, p. 321-340

Short-term effects of unilateral lesion of the primary motor cortex (M1) on ipsilesional hand dexterity in adult macaque monkeys

Bashir, Shahid ; Kaeser, Mélanie ; Wyss, Alexander ; Hamadjida, Adjia ; Liu, Yu ; Bloch, Jocelyne ; Brunet, Jean-François ; Belhaj-Saif, Abderraouf ; Rouiller, Eric M.

In: Brain Structure and Function, 2011, vol. 217, no. 1, p. 63-79

Although the arrangement of the corticospinal projection in primates is consistent with a more prominent role of the ipsilateral motor cortex on proximal muscles, rather than on distal muscles involved in manual dexterity, the role played by the primary motor cortex on the control of manual dexterity for the ipsilateral hand remains a matter a debate, either in the normal function or after a...

Autologous adult cortical cell transplantation enhances functional recovery following unilateral lesion of motor cortex in primates: a pilot study

Kaeser, Melanie ; Brunet, Jean-Francois ; Wyss, Alexander ; Belhaj-Saif, Abderraouf ; Liu, Yu ; Hamadjida, Adjia ; Rouiller, Eric M. ; Bloch, Jocelyne

In: Neurosurgery, 2011, vol. 68, no. 5, p. 1405-1417

BACKGROUND: Although cell therapy is a promising approach after cerebral cortex lesion, few studies assess quantitatively its behavioral gain in nonhuman primates. Furthermore, implantations of fetal grafts of exogenous stem cells are limited by safety and ethical issues.OBJECTIVE: To test in nonhuman primates the transplantation of autologous adult neural progenitor cortical cells with...